The Human Immune System Explorer (HISE) is a powerful tool developed by the Allen Institute for Immunology to analyze, interpret, and share discoveries from studies on the human immune system in both health and disease. Created with a commitment to open science, HISE accelerates immunological research, helping researchers worldwide access and explore critical data. The platform supports collaborative research on vital topics, including SARS-CoV-2, long COVID, autoimmune diseases (such as rheumatoid arthritis and IBD), cancer (multiple myeloma and melanoma), and overall immune health.
Launched in 2018, the Allen Institute for Immunology conducts extensive, longitudinal studies on hundreds of individuals, gathering comprehensive data through blood and tissue samples, advanced genetic sequencing, cell analysis techniques, and protein measurements. The research also incorporates human metadata, covering details like demographics, lifestyle habits, and health history.
HISE is a collaborative effort with partner institutions like the Fred Hutchinson Cancer Research Center, the Benaroya Research Institute, and several leading universities. This platform is more than a data repository; it’s a hub for the scientific community to analyze, interpret, and discuss findings collaboratively, driving forward our understanding of the immune system.
Key Features of the Human Immune System Explorer:
Longitudinal Studies: Tracks individuals over years to understand immune changes across time and conditions.
Open Science Platform: Provides public access to immunological data, aligning with the Allen Institute’s open science commitment.
Collaborative Research: Supports studies on SARS-CoV-2, autoimmune diseases, cancer, and immune health with top research institutions.
Comprehensive Data Collection: Includes genetic sequencing, cell analysis, protein levels, and detailed human metadata.
Multidisciplinary Approach: Integrates insights from immunology, bioinformatics, genetics, and other fields.
